VCBM 15: Eurographics Workshop on Visual Computing for Biology and Medicine

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https://diglib.eg.org/handle/10.2312/13225

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Browsing VCBM 15: Eurographics Workshop on Visual Computing for Biology and Medicine by Subject "Biology and genetics"

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    Discovering Medical Knowledge Using Visual Analytics
    (The Eurographics Association, 2015) Sturm, Werner; Schreck, Tobias; Holzinger, Andreas; Ullrich, Torsten; Katja Bühler and Lars Linsen and Nigel W. John
    Due to advanced technologies, the amount of biomedical data has been increasing drastically. Such large data sets might be obtained from hospitals, medical practices or laboratories and can be used to discover unknown knowledge and to find and reflect hypotheses. Based on this fact, knowledge discovery systems can support experts to make further decisions, explore the data or to predict future events. To analyze and communicate such a vast amount of information to the user, advanced techniques such as knowledge discovery and information visualization are necessary. Visual analytics combines these fields and supports users to integrate domain knowledge into the knowledge discovery process. This article gives a state-of-the-art overview on visual analytics reseach with a focus on the biomedical domain, systems biology and *omics data.
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    FoldSynth: Interactive 2D/3D Visualisation Platform for Molecular Strands
    (The Eurographics Association, 2015) Todd, Stephen; Todd, Peter; Leymarie, Frederic Fol; Latham, William; Kelley, Lawrence A.; Sternberg, Michael; Hugues, Jim; Taylor, Stephen; Katja Bühler and Lars Linsen and Nigel W. John
    FoldSynth is an interactive platform designed to help understand the characteristics and commonly used visual abstractions of molecular strands with an emphasis on proteins and DNA. It uses a simple model of molecular forces to give real time interactive animations of the folding and docking processes. The shape of a molecular strand is shown as a 3D visualisation floating above a 2D triangular matrix representing distance constraints, contact maps or other features of residue pairs. As well as more conventional raster plots, contact maps can be shown with vectors representing the grouping of contacts as secondary structures. The 2D visualisation is also interactive and can be used to manipulate a molecule, define constraints, control and view the folding dynamically, or even design new molecules. While the 3D visualisation is more realistic showing a molecule representation approximating the physical behavior and spatial properties, the 2D visualisation offers greater visibility, in that all molecular positions (and pairings) are always in view; the 3D mode may suffer occlusions and create complex views which are typically hard to understand to humans.