FoldSynth: Interactive 2D/3D Visualisation Platform for Molecular Strands

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dc.contributor.authorTodd, Stephenen_US
dc.contributor.authorTodd, Peteren_US
dc.contributor.authorLeymarie, Frederic Folen_US
dc.contributor.authorLatham, Williamen_US
dc.contributor.authorKelley, Lawrence A.en_US
dc.contributor.authorSternberg, Michaelen_US
dc.contributor.authorHugues, Jimen_US
dc.contributor.authorTaylor, Stephenen_US
dc.contributor.editorKatja Bühler and Lars Linsen and Nigel W. Johnen_US
dc.date.accessioned2015-09-14T04:48:58Z
dc.date.available2015-09-14T04:48:58Z
dc.date.issued2015en_US
dc.description.abstractFoldSynth is an interactive platform designed to help understand the characteristics and commonly used visual abstractions of molecular strands with an emphasis on proteins and DNA. It uses a simple model of molecular forces to give real time interactive animations of the folding and docking processes. The shape of a molecular strand is shown as a 3D visualisation floating above a 2D triangular matrix representing distance constraints, contact maps or other features of residue pairs. As well as more conventional raster plots, contact maps can be shown with vectors representing the grouping of contacts as secondary structures. The 2D visualisation is also interactive and can be used to manipulate a molecule, define constraints, control and view the folding dynamically, or even design new molecules. While the 3D visualisation is more realistic showing a molecule representation approximating the physical behavior and spatial properties, the 2D visualisation offers greater visibility, in that all molecular positions (and pairings) are always in view; the 3D mode may suffer occlusions and create complex views which are typically hard to understand to humans.en_US
dc.description.sectionheadersMolecular Visualization and Visual Analyticsen_US
dc.description.seriesinformationEurographics Workshop on Visual Computing for Biology and Medicineen_US
dc.identifier.doi10.2312/vcbm.20151207en_US
dc.identifier.isbn978-3-905674-82-8en_US
dc.identifier.issn2070-5786en_US
dc.identifier.pages41-50en_US
dc.identifier.urihttps://doi.org/10.2312/vcbm.20151207en_US
dc.publisherThe Eurographics Associationen_US
dc.subjectJ.3 [Computer Applications]en_US
dc.subjectLife and Medical Scienceen_US
dc.subjectBiology and geneticsen_US
dc.titleFoldSynth: Interactive 2D/3D Visualisation Platform for Molecular Strandsen_US
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VCBM 15: Eurographics Workshop on Visual Computing for Biology and Medicine