Evolutionary Pathlines for Blood Flow Exploration in Cerebral Aneurysms

dc.contributor.authorBehrendt, Benjaminen_US
dc.contributor.authorEngelke, Witoen_US
dc.contributor.authorBerg, Philippen_US
dc.contributor.authorBeuing, Oliveren_US
dc.contributor.authorPreim, Bernharden_US
dc.contributor.authorHotz, Ingriden_US
dc.contributor.authorSaalfeld, Sylviaen_US
dc.contributor.editorKozlíková, Barbora and Linsen, Lars and Vázquez, Pere-Pau and Lawonn, Kai and Raidou, Renata Georgiaen_US
dc.date.accessioned2019-09-03T13:49:31Z
dc.date.available2019-09-03T13:49:31Z
dc.date.issued2019
dc.description.abstractBlood flow simulations play an important role for the understanding of vascular diseases, such as aneurysms. However, analysis of the resulting flow patterns, especially comparisons across patient groups, are challenging. Typically, the hemodynamic analysis relies on trial and error inspection of the flow data based on pathline visualizations and surface renderings. Visualizing too many pathlines at once may obstruct interesting features, e.g., embedded vortices, whereas with too little pathlines, particularities such as flow characteristics in aneurysm blebs might be missed. While filtering and clustering techniques support this task, they require the pre-computation of pathlines densely sampled in the space-time domain. Not only does this become prohibitively expensive for large patient groups, but the results often suffer from undersampling artifacts. In this work, we propose the usage of evolutionary algorithms to reduce the overhead of computing pathlines that do not contribute to the analysis, while simultaneously reducing the undersampling artifacts. Integrated in an interactive framework, it efficiently supports the evaluation of hemodynamics for clinical research and treatment planning in case of cerebral aneurysms. The specification of general optimization criteria for entire patient groups allows the blood flow data to be batch-processed. We present clinical cases to demonstrate the benefits of our approach especially in presence of aneurysm blebs. Furthermore, we conducted an evaluation with four expert neuroradiologists. As a result, we report advantages of our method for treatment planning to underpin its clinical potential.en_US
dc.description.sectionheadersBlood Flow and Vascular Visualization
dc.description.seriesinformationEurographics Workshop on Visual Computing for Biology and Medicine
dc.identifier.doi10.2312/vcbm.20191250
dc.identifier.isbn978-3-03868-081-9
dc.identifier.issn2070-5786
dc.identifier.pages253-263
dc.identifier.urihttps://doi.org/10.2312/vcbm.20191250
dc.identifier.urihttps://diglib.eg.org:443/handle/10.2312/vcbm20191250
dc.publisherThe Eurographics Associationen_US
dc.subjectHuman
dc.subjectcentered computing
dc.subjectScientific visualization
dc.titleEvolutionary Pathlines for Blood Flow Exploration in Cerebral Aneurysmsen_US
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